Erection Comparison – how to choose Viagra, Cialis, Levitra

By | June 6, 2019

If you have ever watched the Super Bowl or the World Series, chances are you have already seen an advertisement of Viagra, Levitra, or Cialis. You probably already know the basic information about these three medications, but there is actually a lot more to know in order for you to select which is the one that will work best for you.

All three medications work in the same way. The drugs are all phosphodiesterase type 5 or PDE-5 inhibitors. PDE-5 is an enzyme that breaks down cGMP, which is the chemical responsible for relaxing the muscles along the penis and increasing blood flow in the penis – in effect, creating an erection. The three erectile dysfunction medications all work towards inhibiting PDE-5, which will then keep cGMP levels high enough to supply adequate blood to the penis to create an erection. This also works in women by relaxing the clitoral smooth muscles, also allowing blood to flow into the clitoris.

No matter what the cause of a man’s erectile dysfunction, all three drugs have high success rates in producing erections. In fact, it has been reported that 70-80% of men enjoy satisfactory results from using the medications (NEnglJ Med 1998; 338: 1397).

Women have also benefited from the effects of the drugs. Recently, 200 postmenopausal women with problems in sexual stimulation participated in a placebo-controlled study. For 12 weeks, half of the women were given Viagra, while half received placebo. After the 12 weeks, there was a significant improvement in the sexual experience of the women who used Viagra, except for those who had been previously diagnosed with hypoactive sexual desire (JUrol 2003; 170:2333-2338). This shows that Viagra also improves the sexual sensations for women just like in men, but it does not enhance sexual desire.

PDE-5 inhibitors are very effective for patients, particularly men, with antidepressant-associated sexual dysfunction (AASD). A placebo-controlled study was conducted recently on 90 men with AASD. For 6 weeks, half of the men were given Viagra and the other half received placebo. After the 6-week period, 59% of the men who were given Viagra reported a “very much improved” sexual performance as opposed to only 6% of the men who received placebo. By the end of the six weeks, most of the subjects were taking 100 mg doses. (JAMA 2003; 289: 56-64).

It has been commonly observed that in AASD patients, while there is general satisfaction when it comes to having erections, patients usually complain about experiencing delayed ejaculation. Many men have attested that this problem can be avoided by taking higher doses of PDE-5 inhibitors (PDE-5Is). Based on these claims, Columbia University researchers conducted a study on the possible effects of higher doses of Viagra for AASD-afflicted patients who are experiencing delay in ejaculations.

In the study, subjects were given a low dose of Viagra (25mg) in the beginning and were instructed to continuously increase the dosage until results can be seen. There were 21 men who participated in the study. Four of them responded to doses from 25 – 100 mg. Patients dropped out of the study until only 10 men remained who were still experiencing delay of ejaculation. Nine of the 10 responded to the medication after taking doses of between 150 and 200 mg. This is already twice the FDA’s recommended dosage of 100 mg, but few side effects were reported. (J Clin Psychiatry 2003; 64:721-725).

There are a number of unsuccessful PDE-5I users who could get more response from the medications simply by knowing more about the drugs. Urologists claim that about 40-55% of men who seem to get no results from PDE-5Is can achieve the desired results by changing the way they take the medications and following instructions more concisely (J Urol 2003; 170: 2356-2358). Here are some simple things patients can do to maximize the effects of the PDE-5Is:

Take the recommended dose in the correct time frame which is usually between 30 minutes and 4 hours prior to having any sexual activity.

Take an adequate dose of the medication. If you are taking 50 mg of Viagra, or 10 mg of Levitra or Cialis from https://eddrugs2018.com/generic-cialis, and it does produce any results, double the dosage and see the difference it can make.

Cialis may be taken whether you have eaten anything or not, but Viagra and Levitra must be taken on an empty stomach in order to work.

If the first time does not work, don’t give up right away. Results get better every time, so keep trying.

Although these medications are very effective, they cannot work on their own. You will still need to be aroused sexually for the erection to develop.
The question still remains – which of the three medications is the best? As of this writing, no studies have yet been conducted to compare the effectiveness, side effects, or food interactions of all three PDE-5Is.

Some people claim that Levitra shows results faster than Viagra, and that it can be absorbed better after a meal. All three drugs produce the same side effects except for one or two differences. All three drugs are also not to be mixed with any kind of nitrate. It is also not advisable to mix PDE-5Is with doxazosin, but in Cialis, it is strictly prohibited.